Yufeng Shen is an Associate Professor of Systems Biology and Biomedical Informatics at Columbia University. He received his B.S. in biochemistry and molecular biology from Peking University and his Ph.D. in computational biology from Baylor College of Medicine. At Baylor, Shen led the analysis of the first human genome sequenced by next-generation technologies. Dr. Shen currently directs National Institutes of Health–funded research programs that integrate genomics data to predict functional impact of genetic variation by machine learning and identify genetic causes of human diseases.