Robert C. Green, MD, MPH is Professor of Medicine at Harvard Medical School, and directs the Genomes2People Research Program in translational genomics and health outcomes at Brigham and Women’s Hospital and Broad Institute. He sees patients and conducts empirical research on the medical, behavioral and economic outcomes around the implementation of genomic medicine. With NIH funding, Dr. Green led the first trials disclosing common complex disease risk (REVEAL Study) and the first prospective study of direct-to-consumer genetic testing (PGen Study). He currently leads and co-leads the first randomized trials to explore the implementation of medical sequencing in adults (MedSeq Project) and newborns (BabySeq Project). With support from the Air Force, and in collaboration with military medicine colleagues, he is conducting an exome sequencing implementation study in active duty military personnel (MilSeq Project). Scientific contributions include publication of the first randomized trials to assess the impact of common complex genetic risk markers, empirically measuring the outcomes of DTC genetic testing, design of a variant classification pipeline and single page summary for reporting clinical results of whole genome sequencing. Dr. Green was lead author on the original recommendations for managing incidental findings in clinical sequencing from the American College of Medical Genetics and Genomics and led the first published demonstration of aggregate penetrance of genomic variants in an unselected population. He recently published the first randomized trial to assess appropriateness of care and downstream medical costs of whole genome sequencing in primary care.