Dr. Biesecker is a clinical and molecular geneticist and Chief of the Medical Genomics and Metabolic Branch at the National Human Genome Research Institute of the National Institutes of Health, which he joined in 1993. He uses genetic and genomic technologies to study heritable disorders and has published over 300 primary research articles, reviews, and chapters. His laboratory has elucidated the etiology and natural history of numerous diseases. In addition, he developed the ClinSeq® program, which began clinical genomics research in 2006, before the widespread availability of next generation sequencing. He co-directs a CLIA-certified molecular diagnostic laboratory within NHGRI.
Dr. Biesecker is an editor or board member for several biomedical journals, was a member of the board of directors for the American Society of Human Genetics, and served on the advisory panels for the World Trade Center victim identification effort. He was recently elected to the National Academy of Medicine of the National Academy of Science and has been elected to be the President of the American Society of Human Genetics for 2019.