Slide

GENERAL MEETING

Agenda

2022 Agenda

June 6, 2022

10:30 a.m. – 4:00 p.m.

Bonnet Creek Ballroom Salon I-VI

Pre-Conference

10:00 a.m. – 11:00 a.m.

McDonnell Genome Institute, Washington University
Human Pangenome Reference Consortium (HPRC)

12:00 p.m. – 4:00 p.m.

TBD

Scientific Program

11:00 a.m. – 8:00 p.m.

Bonnet Creek Center Foyer

Meeting Registration

Floridian Ballroom Salon A-L

Plenary Session: Genomics I (Eric Green, National Human Genome Research Institute, Chair)

5:00 p.m. – 5:05 p.m.

Opening Remarks

Richard Wilson, Executive Director, Institute for Genomic Medicine at Nationwide Children’s Hospital, Board Member and Co-Founder of AGBT

5:05 p.m. – 5:35 p.m.

Pardis Sabeti

Harvard University, Harvard School of Public Health, The Broad Institute of Harvard and MIT, and Howard Hughes Medical Institute Investigator

5:35 p.m. – 6:05 p.m.

Olga Troyanskaya

Princeton University, and Deputy Director for Genomics at the Flatiron Institute, Simons Foundation

6:05 p.m. – 6:25 p.m.

William Hwang (Abstract Selected)

Massachusetts General Hospital

“Multicellular spatial neighborhoods in pancreatic cancer are remodeled by neoadjuvant treatment”

6:25 p.m. – 6:55 p.m.

Late breaking abstract, TBA

7:00 p.m. – 10:00 p.m.

Hilton Pool

Welcome Reception

June 7, 2022 (Morning)

7:30 a.m. – 9:00 a.m.

Waldorf Golf Pavilion

Breakfast

8:00 a.m. – 3:00 p.m.

Bonnet Creek Ballroom West Foyer

Meeting Registration

Floridian Ballroom Salon A-L

Plenary Session: Evolutionary Genomics (Beth Shapiro, University of California, Santa Cruz, Chair)

9:00 a.m. – 9:30 a.m.

Mary O’Connell

University of Nottingham, UK

9:30 a.m. – 10:00 a.m.

Simone Immler

University of East Anglia, UK

10:00 a.m. – 10:30 a.m.

Elinor Karlsson

University of Massachusetts Medical School, and director of Vertebrate Genomics at the Broad Institute of MIT and Harvard

10:30 a.m. – 11:00 a.m.

Coffee Break

Sponsor Promenades

11:00 a.m. – 11:20 a.m.

Late breaking abstract, TBA

11:20 a.m. – 11:40 p.m.

Poster Flash Talks

Martin Hirst, University of British Columbia, Chair

June 7, 2022 (Afternoon)

12:00 p.m. – 1:30 p.m.

Bonnet Creek Ballroom Salon I-VI

Gold Sponsor Workshop and Lunch

12:00 p.m. – 1:30 p.m.

Outdoor Waldorf Promenade

AGBT Lunch

1:30 p.m. – 3:00 p.m.

Bonnet Creek Ballroom Salon VII-XII

Poster Session with Coffee & Dessert

Floridian Ballroom Salon A-L

Plenary Session: Genomics II

Martin Hirst, University of British Columbia, Chair

3:00 p.m. – 3:30 p.m.

Trevor Lawley

Wellcome Sanger Institute and Chief Scientific Officer, Microbiotica

3:30 p.m. – 4:00 p.m.

Alison Van Eenennaam

University of California, Davis

4:00 p.m. – 4:20 p.m.

Samantha Zarate (Abstract Selected)

Johns Hopkins University

“A complete reference genome improves analysis of human genetic variation”

4:20 p.m. – 4:40 p.m.

Late breaking abstract, TBA

June 7, 2022 (Evening)

5:00 p.m. – 7:15 p.m.

Dinner on your own

5:30 p.m. – 7:15 p.m.

Signature Island

Women’s Networking Event

Bonnet Creek Ballroom Salon I-VI

Concurrent Session: Cancer

Kim Doheny, Johns Hopkins Institute of Genetic Medicine, Chair

7:30 p.m. – 7:50 p.m.

Billy Lau, Stanford University School of Medicine

“Massively parallel nanopore sequencing of circulating tumor DNA enables robust quantification of tumor burden”

7:50 p.m. – 8:10 p.m.

Quan Nguyen, Institute for Molecular Bioscience, The University of Queensland

“Building a spatial single-cell multi-omics atlas and cellular interactome for skin cancer”

8:10 p.m. – 8:30 p.m.

Michael Quail, Wellcome Sanger Institute

“NanoSeq: A high-throughput pipeline for the detection of somatic mutations at single-molecule resolution”

8:30 p.m. – 8:50 p.m.

Lukas Chavez, University of California, San Diego

“The landscape of extrachromosomal circular DNA in medulloblastoma”

8:50 p.m. – 9:10 p.m.

Edwin Cuppen, Hartwig Medical Foundation

“Routine whole genome sequencing-based cancer diagnostics for precision medicine”

9:10 p.m. – 9:30 p.m.

Jean-Christophe Marine, VIB

“Dissecting the melanoma ecosystem at single-cell resolution using Molecular CartographyTM”

Floridian Ballroom Salon A-L

Concurrent Session: Computational Biology

Mike Zody, New York Genome Center, Chair

7:30 p.m. – 7:50 p.m.

Kristian Cibulskis, The Broad Institute

“Optimizing large-scale joint callsets for All of Us”

7:50 p.m. – 8:10 p.m.

Melanie Kirsche, Johns Hopkins University

“Jasmine: Population-scale structural variant comparison and analysis”

8:10 p.m. – 8:30 p.m.

Mathieu Bourgey, McGill University

“A system biology approach identifies candidate drugs to reduce mortality in severely ill COVID-19 patients”

8:30 p.m. – 8:50 p.m.

Tanner Jensen, Stanford University

“Integrative analysis of long-read and functional genomics data improves prioritization of pathogenic variants in exome-negative, rare-disease patients”

8:50 p.m. – 9:10 p.m.

Jialong Jiang, California Institute of Technology

“Spin-network models identify and predict human immunomodulatory drug response signatures in high-throughput single-cell mRNA-seq data”

9:10 p.m. – 9:30 p.m.

Chandrima Bhattacharya, Weill Cornell Medicine

“Microbial survival in the Anthropocene: Bioremediation and biomining potential of a superfund site – the Gowanus Canal”

9:30 p.m.

CLICK2WIN (Formerly Passport to Prizes)

Sponsor Promenades

June 8, 2022 (Morning)

7:30 a.m. – 9:00 a.m.

Waldorf Golf Pavilion

Breakfast

Floridian Ballroom Salon A-L

Plenary Session: Genetics I

Federica Di Palma, Genome British Columbia, Chair

9:00 a.m. – 9:30 a.m.

Euan Ashley

Stanford University

9:30 a.m. – 10:00 a.m.

Neil Hanchard

National Human Genome Research Institute

10:00 a.m. – 10:20 a.m.

Lesley Shirley (Abstract Selected)

Wellcome Sanger Institute

“Large-scale whole-genome sequencing of SARS-CoV-2 at the Sanger Institute: The COVID-19 Genomics UK consortium”

10:20 a.m. – 11:00 a.m.

Coffee Break

Sponsor Promenade

11:00 a.m. – 11:20 a.m.

Late breaking abstract, TBA

11:20 a.m. – 11:40 a.m.

Poster Flash Talks

June 8, 2022 (Afternoon)

12:00 p.m. – 2:00 p.m.

Bonnet Creek Ballroom Salon I-VI

Silver Sponsor Workshops

12:00 p.m.  –  1:00 p.m.

Silver Sponsor

1:05 p.m.  –  2:05 p.m.

Silver Sponsor

12:00 p.m. – 2:00 p.m.

Outdoor Waldorf Promenade

AGBT Lunch

Floridian Ballroom Salon A-L

Bronze Sponsor Workshops

Stephen Montgomery, Stanford University School of Medicine, Chair

2:15 p.m. – 2:35 p.m.

2:35 p.m. – 2:55 p.m.

2:55 p.m. – 3:15 p.m.

3:15 p.m. – 3:30 p.m.

3:30 p.m. – 3:45 p.m.

3:45 p.m. – 4:00 p.m.

4:00 p.m. – 4:15 p.m.

4:15 p.m. – 4:27 p.m.

4:27 p.m. – 4:39 p.m.

4:40 p.m. – 6:10 p.m.

Bonnet Creek Ballroom Salon VII-XII

Poster Session and Wine Reception

June 8, 2022 (Evening)

6:15 p.m. – 7:25 p.m.

Outdoor Waldorf Promenade

AGBT Dinner

Floridian Ballroom Salon A-L

Concurrent Session: Technology

Chris Mason, Weill Cornell Medicine, Chair

7:30 p.m. – 7:50 p.m.

Chongyuan Luo, University of California, Los Angeles

“In situ single-cell epigenomic profiling by photonic-indexing sequencing”

7:50 p.m. – 8:10 p.m.

Sheridan Cavalier, Johns Hopkins School of Medicine Dept of Neuroscience

“Single-cell transcript isoform sequencing of the actived adult mouse hippocampus with 10x Genomics and Oxford Nanopore”

8:10 p.m. – 8:30 p.m.

George Emanuel, Vizgen

“Molecular atlassing with MERSCOPE: A new spatial transcriptomics technique accurately reveals the organization of the mouse brain transcriptome”

8:30 p.m. – 8:50 p.m.

Heonseok Kim, Stanford University

“A single cell CRISPR and nanopore long read approach for modifying mRNA sequence and generating novel transcript isoforms”

8:50 p.m. – 9:10 p.m.

Joshua Cohen, Johns Hopkins University School of Medicine

“Detection of low-frequency DNA variants by targeted sequencing of the Watson and Crick strands”

9:10 p.m. – 9:30 p.m.

Joseph Beechem, Nanostring Technologies Inc.

“High-plex (> 1000), multi-omic (RNA plus protein), spatial molecular imaging with sub-cellular resolution in FFPE tissue”

Bonnet Creek Ballroom Salon I-VI

Concurrent Session: Biology  

7:30 p.m. – 7:50 p.m.

Jeffrey Shaman, Coriell Life Sciences

“Results and reflections of a real-world implementation of a pharmacogenomics-empowered comprehensive medication management (CMM) program”

7:50 p.m. – 8:10 p.m.

TBD

8:10 p.m. – 8:30 p.m.

Varuna Chander, Baylor College of Medicine

“Somatic mosaicism and cardiovascular disease: Uncovering hidden genetic etiology with clinical Implications”

8:30 p.m. – 8:50 p.m.

Eloi Schmauch, Massachusetts Institute of Technology, University of Eastern Finland, MIT and Harvard, Broad Institute

“Single-cell spatio-transcriptional dissection of human heart in health and coronary artery disease reveals cell-type-specific driver genes and pathways”

8:50 p.m. – 9:10 p.m.

Ethan Winkler, Barrow Neurologic Institute

“A cell resolution atlas of the human cerebrovasculature”

8:50 p.m. – 9:10 p.m.

Hilde Nelissen, Ghent University, Department of Plant Biotechnology and Bioinformatics / VIB Center for Plant Systems Biology

“Molecular CartographyTM reveals novel cell types and gene functions in the maize shoot apex”

June 9, 2022 (Morning)

7:30 a.m. – 9:00 a.m.

Waldorf Golf Pavilion

Breakfast

Floridian Ballroom Salon A-L

Plenary Session: Genetics II

Len Pennacchio, Lawrence Berkeley National Laboratory and DOE Joint Genome Institute, Chair

9:00 a.m. – 9:30 a.m.

Zach Lippman

Cold Spring Harbor Laboratory (CSHL) and Howard Hughes Medical Institute (HHMI)

9:30 a.m. – 10:00 a.m.

Alicia Zhou

Chief Science Officer, Color

10:00 a.m. – 10:20 a.m.

CA / University of East Anglia, UK

“Evolution of regulatory networks associated with traits under selection in cichlids”

10:20 a.m. – 11:00 a.m.

Coffee Break

Sponsor Promenades

11:10 a.m. – 11:30 a.m.

Konrad Karczewski (Abstract Selected)

The Broad Institute

Systematic single-variant and gene-based association testing of 3,700 phenotypes in 281,850 UK Biobank exomes

11:30 a.m. – 11:50 a.m.

Late breaking abstract, TBA

12:00 p.m. – 1:00 p.m.

Bonnet Creek Ballroom Salon I-VI

Silver Sponsor Workshop

12:00 p.m. – 1:30 p.m.

Outdoor Waldorf Promenade

AGBT Lunch

June 9, 2022 (Afternoon)

Floridian Ballroom Salon A-L

Plenary Session:  Technology II

John McPherson, University of California, Davis, Chair

1:30 p.m. – 2:00 p.m.

Fei Chen

The Broad Institute of MIT and Harvard

2:00 p.m. – 2:30 p.m.

TBA

2:30 p.m. – 2:50 p.m.

 TBA

2:50 p.m. – 3:20 p.m

Floridian Ballroom Foyer

Coffee Break

3:20 p.m. – 3:50 p.m.

Ghamdan Al-Eryani (Abstract Selected)

Garvan Institute of Medical Research

“Multi-omic integration of single-cell and spatial RNA and protein analysis identifies novel tumor-infiltrating lymphocyte phenotypes”

3:50 p.m. – 4:10 p.m.

Late breaking abstract, TBA

4:10 p.m. – 4:15 p.m.

CLICK2WIN Winner Announced

4:15 p.m. – 4:30 p.m.

Closing Comments and Meeting Feedback

6:00 p.m. – 11:00 p.m.

Waldorf Golf Pavilion

Farewell Dinner Party

Mardi Gras Theme

Join us at AGBT’s flagship event for bringing together global leaders, researchers, and innovators.