GENERAL MEETING

Agenda
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2020 Agenda

Preview the General Meeting agenda to explore a wealth of stimulating presentations, interactive workshops,
dedicated networking sessions, and more. 2021 agenda coming soon.

DAY 1 – SUNDAY, FEBRUARY 23

Scientific Program

10:30 AM – 4:00 PM

Calusa Ballroom 1–5

Pre-Conference

10:30 AM – 11:30 AM

McDonnell Genome Institute,
Washington University-Human Pangenome
Reference Consortium (HPRC)

12:00 PM – 4:00 PM

NanoString
2nd Annual Spatial Genomics Summit

11:00 AM – 8:00 PM

Calusa Ballroom Foyer

Meeting Registration

Calusa Ballroom 6–12

Genomics I – Plenary Session

ERIC GREEN

National Human Genome Research Institute, Chair

5:00 PM – 5:05 PM

Opening Remarks

Richard Wilson

Executive Director, The Institute for Genomic Medicine at Nationwide Children’s Hospital, Board Member and Co-Founder of AGBT

5:05 PM – 5:35 PM

Francis Collins

National Institutes of Health (NIH)

Two decades of breathtaking progress in genomics – but the best is yet to come

5:35 PM – 6:05 PM

Barbara Wold

California Institute of Technology

6:05 PM – 6:25 PM

Carrie Cibulskis*

The Broad Institute of MIT and Harvard

Liquid biopsy assays for the next generation of personalized cancer treatment

6:25 PM – 6:45 PM

Asaf Rotem*

Dana Farber Cancer Institute

Single-cell analysis of the malignant ascites ecosystem provides cues for classification of ovarian cancer and potential therapeutic avenues

Abstract Selected Talk *

Day 2 - Monday, February 24

7:30 AM – 9:00 AM

Sunset Terrace

Breakfast

8:00 AM – 3:00 PM

Calusa Ballroom Foyer

Meeting Registration

Calusa Ballroom 6–12

Technology I – Plenary Session

BETH SHAPIRO

University of California, Santa Cruz, Chair

9:00 AM – 9:30 AM

Leroy Hood

PROVIDENCE HEALTH & SERVICES

21st Century Medicine: Systems Biology, Big Data and Deep Phenotyping

9:30 AM – 10:00 AM

Barbara Rae-Venter

Director, Investigative Genetic Genealogy, Gene by Gene

Investigative genetic genealogy

10:00 AM – 10:20 AM

Matthew Keller*

Centers for Disease Control and Prevention

Portable influenza A virus diagnostics and surveillance

10:20 AM – 11:00 AM

Sponsors’ Promenade

Coffee Break

11:00 AM – 11:20 AM

George Church*

Harvard University

Technologies for reading and writing omes

11:20 AM – 11:40 AM

Poster Flash Talks*

MARTIN HIRST

University of British Columbia, Chair

1:30 PM – 3:00 PM

Banyan & Calusa Ballroom Foyers Levels 1 and 3

Poster Session with Coffee & Dessert

12:00 PM – 1:30 PM

Banyan Ballroom

10X Genomics Gold Sponsor Workshop

Complementary Lunch Provided

Explore Biology Like Never Before

12:00 PM – 1:30 PM

Sunset Terrace

AGBT Lunch

1:30 PM – 3:00 PM

Banyan & Calusa Ballroom Foyers Levels 1 and 3

Poster Session with Coffee & Dessert

Calusa Ballroom 6–12

Genomics II – Plenary Session

Len Pennacchio

Lawrence Berkeley National Laboratory, Chair

3:00 PM – 3:30 PM

Catherine Ball

ANCESTRY DNA

Bringing genome sequencing into the consumer marketplace

3:30 PM – 4:00 PM

Richard Myers

HudsonAlpha Institute

Genomics, gene regulation and the human brain

3:30 PM – 4:00 PM

David Danko*

Weill Cornell Medicine of Cornell University

Global genetic cartography of urban metagenomes and antimicrobial resistance”

4:20 PM – 4:40 PM

Deanna Church*

Inscripta, Inc

A benchtop platform for generating highly multiplexed variant libraries

5:20 PM – 7:15 PM

Dinner On Your Own

5:30 PM – 7:15 PM

Calusa Terrace

Women’s Networking Event

Calusa Ballroom 6–12

Informatics – Concurrent Session

Mike Zody

New York Genome Center, Chair

4:20 PM – 4:40 PM

Francisco De La Vega

Fabric Genomics

Benchmarking an artificial intelligence method for fast diagnosis of rare genetic disease

7:50 PM – 8:10 PM

David Craig

University of Southern California

Integrative analysis and visualization of spatial transcriptomics data In oncology and neuroscience settings

8:10 PM – 8:30 PM

Yaniv Erlich

Columbia University/MyHeritage

The DNA of things

8:30 PM – 8:50 PM

Uday Evani

New York Genome Center

High coverage whole genome sequencing of 2504 samples from the 1000 Genomes Project

8:50 PM – 9:10 PM

Amnon Koren

Cornell University

Inferring human DNA replication timing en masse in thousands of samples

9:10 PM – 9:30 PM

Sara Selitsky

University of North Carolina at Chapel Hill

Fast clustering millions of single cells

Calusa Ballroom 1–5

Cancer – Concurrent Session

Stephen Montgomery

Stanford University School of Medicine, Chair

7:30 PM – 7:50 PM

Catherine Cottrell

Nationwide Children’s Hospital

Enrichment of Targetable Gene Fusion Events and their Associated Impact in a Pediatric Cancer Population

7:50 PM – 8:10 PM

William Hwang

The Broad Institute of MIT and Harvard

Single-nucleus RNA-seq reveals distinct intratumoral transcriptomic heterogeneity in treatment-naïve and chemoradiotherapy-treated primary pancreatic ductal adenocarcinoma

8:10 PM – 8:30 PM

Marcin Imielinski

Weill Cornell Medicine of Cornell University

Unraveling the allelic structure around recurrent complex structural variant patterns in cancer using optical mapping and linked-reads

8:30 PM – 8:50 PM

Maija Kiuru

University of California Davis

Identification of cell type-specific RNA biomarker candidates in melanocytic tumors using digital spatial profiling

8:50 PM – 9:10 PM

Richard Moore

Canada’s Michael Smith Genome Sciences Centre

Whole genome and transcriptome sequencing for personalized cancer therapy

9:10 PM – 9:30 PM

Deep Pandya

Danbury Hospital

Clonal cancer-mutations but without clinical disease: Cancer-driver gene mutations are nearly ubiquitous in uterine tissue from women without cancer

9:30 PM

Sponsors’ Promenades & Lanai Suites

Passport to Prizes

Abstract Selected Talk *

DAY 3 – TUESDAY, FEBRUARY 25

7:30 AM – 9:00 AM

Sunset Terrace

Breakfast

Calusa Ballroom 6–12

Genetics I – Plenary Session

Kim Doheny

Johns Hopkins Department of Genetic Medicine, Chair

9:00 AM – 9:30 AM

Richard Wilson

Institute for Genomic Medicine, Nationwide Children’s Hospital

Advances in cancer genomics

9:30 AM – 10:00 AM

Marco Marra

Michael Smith Genome Sciences Centre

Towards a Canadian national program for genomic profiling of treatment resistant cancers.

10:00 AM – 10:20 AM

Kathryn Geiger-Schuller*

The Broad Institute of MIT and Harvard

Relating thousands of variants to function with massively parallel pooled genetic screens

10:20 AM – 11:00 AM

Sponsor Promenades

Coffee Break

11:00 AM – 11:20 AM

Xiaowu Gai*

Children’s Hospital of Los Angeles

Dynamic encryption and watermarking of genomic sequencing data to facilitate privacy-preserving ownership-based data governance

11:20 AM – 11:40 AM

Poster Flash Talks

Federica Di Palma

Earlham Institute, University of East Anglia, Chair

Banyan Ballroom

12:00 PM – 2:00 PM

Silver Sponsor Workshop

COMPLEMENTARY LUNCH PROVIDED

Sunset Terrace

12:00 PM – 2:00 PM

AGBT Lunch

12:00 PM – 1:00 PM

Twist Bioscience

Catherine Foo, Ph.D., Director of Laboratory Sciences at Ancestry

Success Never Settles”

1:05 PM – 2:05 PM

Illumina

Gary Schroth, Ph.D., Distinguished Scientist, Illumina, Inc

Transforming the Future of Genomics, Together

12:00 PM – 2:00 PM

Sunset Terrace

AGBT Lunch

Calusa Ballroom 6–12

Bronze Sponsor Workshops

John McPherson

University of California, Davis, Chair

2:15 PM – 2:35 PM

ReadCoor

Richard Terry, Founder, Chief Executive Officer & CTO, ReadCoor

Location Matters: A novel platform for true multi-omic spatial sequencing

2:35 PM – 2:55 PM

Tecan

George Weinstock, Professor, Director for Microbial Genomics at Jackson Laboratory for Genomics Medicine

Microbiome research perspectives and challenges

2:55 PM – 3:15 PM

Roche

Markos Mihalatos, PhD, International Product Manager, Sample Prep Reagents at Roche Sequencing Solutions

Roche’s new target enrichment portfolio: Better by design

3:15 PM – 3:30 PM

NEB

Nicole Lambert, Ph.D., Director of Research, Lexent Bio

Monitoring cell-free methylation changes with enzymatic conversion to assess response to cancer treatment

3:30 PM – 3:45 PM

Twinstrand

Jesse Salk MD, Ph

One-in-ten-million: Using Duplex Sequencing to measure ultra-rare mutations caused by carcinogens, aging and for precision cancer diagnostics.

3:45 PM – 4:00 PM

PerkinElmer

Arvind Kothandaraman, General Manager, Next Generation Sequencing, PerkinElmer

Doing more with less

4:00 PM – 4:15 PM

Miroculus

Fay Christodoulou, PhD, CSO, Miroculus

A novel microfluidic library preparation platform enables multi-omics studies in any laboratory setting

4:15 PM – 4:27 PM

Bluebee

Hans Cobben, CEO, BlueBee

Data science and flows: the sea-change opportunity for genomics

4:27 PM – 4:39 PM

Promega

Gabriela Saldanha, Product Manager, Promega Corporation

Take control of your experiments! Sanger sequencing right at your benchtop with single-base resolution and 6-dye multiplex performance, in a compact and flexible platform

4:40 PM – 6:10 PM

Banyan & Calusa Ballroom Foyers,Levels 1 & 3

Poster Session and Wine Reception

6:15 PM – 7:25 PM

On the Beach

AGBT Dinner

Calusa Ballroom 6–12

Technology – Concurrent Session

Martin Hirst

University of British Columbia, Chair

7:30 PM – 7:50 PM

Xin Jin

Harvard University

In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with Autism risk genes

7:50 PM – 8:10 PM

Chongyuan Luo

University of California Los Angeles

Multi-omic profiling of single nuclei uncovers regulatory diversity of brain cell types and diseases

8:10 PM – 8:30 PM

Laura Mincarelli

Earlham Institute

Integrated short and long read single cell RNA-sequencing reveals alternative splicing events in hematopoietic stem and progenitor cells

8:30 PM – 8:50 PM

Martin Strazar

The Broad Institute of MIT and Harvard

Molecular dynamics of the subcellular transcriptome: a contribution of nuclear and cytoplasmic RNAs to neuronal phenotype and identity

8:30 PM – 8:50 PM

Sanja Vickovic

The Broad Institute of MIT and Harvard

High-definition spatial transcriptomics for in situ tissue profiling

9:10 PM – 9:30 PM

Christopher Mason

Weill Cornell Medicine of Cornell University

Diplotype-resolved, single-molecule telomere sequencing reveals elongation during spaceflight, radiation damage, and non-canonical repeats

Calusa Ballroom 1–5

Biology – Concurrent Session

Federica Di Palma

Earlham Institute, University of East Anglia, Chair

7:30 PM – 7:50 PM

Brenda Oppert

United States Department of Agriculture

Feed the World: Developing genomic resources for insects as food

7:50 PM – 8:10 PM

Andrea Kohn

University of Florida

Molecular architecture of the earliest branching bilaterian – Xenoturbella

8:10 PM – 8:30 PM

Niels Tommerup

University of Copenhagen

Evolutionary conserved topological associating domains define high risk genomic regions for long range dysregulation

8:30 PM – 8:50 PM

Brendan Keating

University of Pennsylvania

Concept, design and implementation of a pilot pharmacogenomics program between UnitedHealth Group and academic clinicians/scientists

8:50 PM – 9:10 PM

Adam Ameur

Science for Life Laboratory

Studying CRISPR guide RNA specificity by amplification-free long read sequencing

9:10 PM – 9:30 PM

Tina Lindsay

McDonnell Genome Institute at Washington University

Generating high quality human reference assemblies

Abstract Selected Talk *

DAY 4 – WEDNESDAY, FEBRUARY 26

7:30 AM – 9:00 AM

Sunset Terrace

Breakfast

Calusa Ballroom 6–12

Genetics II – Plenary Session

Penelope Bonnen

Baylor College of Medicine, Chair

9:00 AM – 9:30 AM

John Novembre

University of Chicago

New tools for the analysis and visualization of geographic structure in population genetic data

9:30 AM – 10:00 AM

Mary Armanios

Johns Hopkins University School of Medicine

The Telomere Syndromes: A paradigm for molecular medicine

10:00 AM – 10:30 AM

Jennifer Fogarty

NASA Human Research Program

NASA Human Research Program: Omics informing human health and performance for space exploration

10:30 AM – 11:10 AM

Sponsor Promenades

Coffee Break

11:10 AM – 11:30 AM

Brandon LaBarge*

Penn State Health

Optical genomic mapping identifies the structure of human papillomavirus genomes in head and neck cancers

11:30 AM – 11:50 AM

Sisi Chen*

California Institute of Technology

Probing multicellular mechanisms of immune modulation with massively parallel single-cell mRNA-seq

2:00 PM – 2:30 PM

Scott Tighe

UVM Integrative Genomics

Genomic strategies for profiling extreme and novel environments

Calusa Ballroom 6–12

Technology II – Plenary Session

Christopher Mason

Weill Cornell Medicine, Chair

Sunset Terrace

12:00 PM – 1:30 PM

AGBT Lunch

Banyan Ballroom

12:00 PM – 1:00 PM

NanoString Silver Sponsor Workshop

Complementary Lunch Provided

Joseph M. Beechem, Chief Scientific Officer and SVP of R&D NanoString Technologies

Yue Lu, PhD, Institute for Systems Biology (ISB)

Krisztian Homicsko, MD, MSc, PhD, CHUV, Ludwig Cancer Research

Expanding high-plex, spatially-resolved in situ RNA expression profiling with NanoString GeoMx™ Digital Spatial Profiler

1:30 PM – 2:00 PM

Sarah Teichmann

Wellcome Sanger Institute

Cell Atlas Technologies & Deciphering Thymic Development

2:00 PM – 2:30 PM

Scott Tighe

UVM Integrative Genomics

Genomic strategies for profiling extreme and novel environments

2:30 PM – 2:50 PM

Shawn Levy*

HudsonAlpha Institute for Biotechnology

Forensic identification and profiling with genomic technologies

2:50 PM – 3:30 PM

Calusa Ballroom Foyer

Coffee Break

3:30 PM – 3:50 PM

David Sinclair*

Harvard Medical School

Epigenetic entropy as a cause of aging and its reversal by Tet-dependent reprogramming

3:50 PM – 4:10 PM

Rade Drmanac*

MGI Americas Inc

First $100 genome sequencing enabled by new extreme throughput DNBSEQ platform

4:10 PM – 4:15 PM

Passport Grand Prize Winner Announced

4:15 PM – 4:30 PM

Closing Comments and Meeting Feedback

7:00 PM – 10:00 PM

Banyan Ballroom

Farewell Dinner Party

Abstract Selected Talk *

Join us at AGBT’s flagship event for bringing together global leaders, researchers, and innovators.