2022 Agenda
June 6, 2022
10:30 a.m. – 4:00 p.m.
Bonnet Creek Ballroom Salon I-VI
Pre-Conference
10:00 a.m. – 11:00 a.m.
McDonnell Genome Institute, Washington University
Human Pangenome Reference Consortium (HPRC)
12:00 p.m. – 4:00 p.m.
TBD
Scientific Program
11:00 a.m. – 8:00 p.m.
Bonnet Creek Center Foyer
Meeting Registration
Floridian Ballroom Salon A-L
Plenary Session: Genomics I (Eric Green, National Human Genome Research Institute, Chair)
5:00 p.m. – 5:05 p.m.
Opening Remarks
Richard Wilson, Executive Director, Institute for Genomic Medicine at Nationwide Children’s Hospital, Board Member and Co-Founder of AGBT
5:05 p.m. – 5:35 p.m.
Pardis Sabeti
Harvard University, Harvard School of Public Health, The Broad Institute of Harvard and MIT, and Howard Hughes Medical Institute Investigator
5:35 p.m. – 6:05 p.m.
Olga Troyanskaya
Princeton University, and Deputy Director for Genomics at the Flatiron Institute, Simons Foundation
6:05 p.m. – 6:25 p.m.
William Hwang (Abstract Selected)
Massachusetts General Hospital
“Multicellular spatial neighborhoods in pancreatic cancer are remodeled by neoadjuvant treatment”
6:25 p.m. – 6:55 p.m.
Late breaking abstract, TBA
7:00 p.m. – 10:00 p.m.
Hilton Pool
Welcome Reception
June 7, 2022 (Morning)
7:30 a.m. – 9:00 a.m.
Waldorf Golf Pavilion
Breakfast
8:00 a.m. – 3:00 p.m.
Bonnet Creek Ballroom West Foyer
Meeting Registration
Floridian Ballroom Salon A-L
Plenary Session: Evolutionary Genomics (Beth Shapiro, University of California, Santa Cruz, Chair)
9:00 a.m. – 9:30 a.m.
Mary O’Connell
University of Nottingham, UK
9:30 a.m. – 10:00 a.m.
Simone Immler
University of East Anglia, UK
10:00 a.m. – 10:30 a.m.
Elinor Karlsson
University of Massachusetts Medical School, and director of Vertebrate Genomics at the Broad Institute of MIT and Harvard
10:30 a.m. – 11:00 a.m.
Coffee Break
Sponsor Promenades
11:00 a.m. – 11:20 a.m.
Late breaking abstract, TBA
11:20 a.m. – 11:40 p.m.
Poster Flash Talks
Martin Hirst, University of British Columbia, Chair
June 7, 2022 (Afternoon)
12:00 p.m. – 1:30 p.m.
Bonnet Creek Ballroom Salon I-VI
Gold Sponsor Workshop and Lunch
12:00 p.m. – 1:30 p.m.
Outdoor Waldorf Promenade
AGBT Lunch
1:30 p.m. – 3:00 p.m.
Bonnet Creek Ballroom Salon VII-XII
Poster Session with Coffee & Dessert
Floridian Ballroom Salon A-L
Plenary Session: Genomics II
Martin Hirst, University of British Columbia, Chair
3:00 p.m. – 3:30 p.m.
Trevor Lawley
Wellcome Sanger Institute and Chief Scientific Officer, Microbiotica
3:30 p.m. – 4:00 p.m.
Alison Van Eenennaam
University of California, Davis
4:00 p.m. – 4:20 p.m.
Samantha Zarate (Abstract Selected)
Johns Hopkins University
“A complete reference genome improves analysis of human genetic variation”
4:20 p.m. – 4:40 p.m.
Late breaking abstract, TBA
June 7, 2022 (Evening)
5:00 p.m. – 7:15 p.m.
Dinner on your own
5:30 p.m. – 7:15 p.m.
Signature Island
Women’s Networking Event
Bonnet Creek Ballroom Salon I-VI
Concurrent Session: Cancer
Kim Doheny, Johns Hopkins Institute of Genetic Medicine, Chair
7:30 p.m. – 7:50 p.m.
Billy Lau, Stanford University School of Medicine
“Massively parallel nanopore sequencing of circulating tumor DNA enables robust quantification of tumor burden”
7:50 p.m. – 8:10 p.m.
Quan Nguyen, Institute for Molecular Bioscience, The University of Queensland
“Building a spatial single-cell multi-omics atlas and cellular interactome for skin cancer”
8:10 p.m. – 8:30 p.m.
Michael Quail, Wellcome Sanger Institute
“NanoSeq: A high-throughput pipeline for the detection of somatic mutations at single-molecule resolution”
8:30 p.m. – 8:50 p.m.
Lukas Chavez, University of California, San Diego
“The landscape of extrachromosomal circular DNA in medulloblastoma”
8:50 p.m. – 9:10 p.m.
Edwin Cuppen, Hartwig Medical Foundation
“Routine whole genome sequencing-based cancer diagnostics for precision medicine”
9:10 p.m. – 9:30 p.m.
Jean-Christophe Marine, VIB
“Dissecting the melanoma ecosystem at single-cell resolution using Molecular CartographyTM”
Floridian Ballroom Salon A-L
Concurrent Session: Computational Biology
Mike Zody, New York Genome Center, Chair
7:30 p.m. – 7:50 p.m.
Kristian Cibulskis, The Broad Institute
“Optimizing large-scale joint callsets for All of Us”
7:50 p.m. – 8:10 p.m.
Melanie Kirsche, Johns Hopkins University
“Jasmine: Population-scale structural variant comparison and analysis”
8:10 p.m. – 8:30 p.m.
Mathieu Bourgey, McGill University
“A system biology approach identifies candidate drugs to reduce mortality in severely ill COVID-19 patients”
8:30 p.m. – 8:50 p.m.
Tanner Jensen, Stanford University
“Integrative analysis of long-read and functional genomics data improves prioritization of pathogenic variants in exome-negative, rare-disease patients”
8:50 p.m. – 9:10 p.m.
Jialong Jiang, California Institute of Technology
“Spin-network models identify and predict human immunomodulatory drug response signatures in high-throughput single-cell mRNA-seq data”
9:10 p.m. – 9:30 p.m.
Chandrima Bhattacharya, Weill Cornell Medicine
“Microbial survival in the Anthropocene: Bioremediation and biomining potential of a superfund site – the Gowanus Canal”
9:30 p.m.
CLICK2WIN (Formerly Passport to Prizes)
Sponsor Promenades
June 8, 2022 (Morning)
7:30 a.m. – 9:00 a.m.
Waldorf Golf Pavilion
Breakfast
Floridian Ballroom Salon A-L
Plenary Session: Genetics I
Federica Di Palma, Genome British Columbia, Chair
9:00 a.m. – 9:30 a.m.
Euan Ashley
Stanford University
9:30 a.m. – 10:00 a.m.
Neil Hanchard
National Human Genome Research Institute
10:00 a.m. – 10:20 a.m.
Lesley Shirley (Abstract Selected)
Wellcome Sanger Institute
“Large-scale whole-genome sequencing of SARS-CoV-2 at the Sanger Institute: The COVID-19 Genomics UK consortium”
10:20 a.m. – 11:00 a.m.
Coffee Break
Sponsor Promenade
11:00 a.m. – 11:20 a.m.
Late breaking abstract, TBA
11:20 a.m. – 11:40 a.m.
Poster Flash Talks
June 8, 2022 (Afternoon)
12:00 p.m. – 2:00 p.m.
Bonnet Creek Ballroom Salon I-VI
Silver Sponsor Workshops
12:00 p.m. – 1:00 p.m.
Silver Sponsor
1:05 p.m. – 2:05 p.m.
Silver Sponsor
12:00 p.m. – 2:00 p.m.
Outdoor Waldorf Promenade
AGBT Lunch
Floridian Ballroom Salon A-L
Bronze Sponsor Workshops
Stephen Montgomery, Stanford University School of Medicine, Chair
2:15 p.m. – 2:35 p.m.
2:35 p.m. – 2:55 p.m.
2:55 p.m. – 3:15 p.m.
3:15 p.m. – 3:30 p.m.
3:30 p.m. – 3:45 p.m.
3:45 p.m. – 4:00 p.m.
4:00 p.m. – 4:15 p.m.
4:15 p.m. – 4:27 p.m.
4:27 p.m. – 4:39 p.m.
4:40 p.m. – 6:10 p.m.
Bonnet Creek Ballroom Salon VII-XII
Poster Session and Wine Reception
June 8, 2022 (Evening)
6:15 p.m. – 7:25 p.m.
Outdoor Waldorf Promenade
AGBT Dinner
Floridian Ballroom Salon A-L
Concurrent Session: Technology
Chris Mason, Weill Cornell Medicine, Chair
7:30 p.m. – 7:50 p.m.
Chongyuan Luo, University of California, Los Angeles
“In situ single-cell epigenomic profiling by photonic-indexing sequencing”
7:50 p.m. – 8:10 p.m.
Sheridan Cavalier, Johns Hopkins School of Medicine Dept of Neuroscience
“Single-cell transcript isoform sequencing of the actived adult mouse hippocampus with 10x Genomics and Oxford Nanopore”
8:10 p.m. – 8:30 p.m.
George Emanuel, Vizgen
“Molecular atlassing with MERSCOPE: A new spatial transcriptomics technique accurately reveals the organization of the mouse brain transcriptome”
8:30 p.m. – 8:50 p.m.
Heonseok Kim, Stanford University
“A single cell CRISPR and nanopore long read approach for modifying mRNA sequence and generating novel transcript isoforms”
8:50 p.m. – 9:10 p.m.
Joshua Cohen, Johns Hopkins University School of Medicine
“Detection of low-frequency DNA variants by targeted sequencing of the Watson and Crick strands”
9:10 p.m. – 9:30 p.m.
Joseph Beechem, Nanostring Technologies Inc.
“High-plex (> 1000), multi-omic (RNA plus protein), spatial molecular imaging with sub-cellular resolution in FFPE tissue”
Bonnet Creek Ballroom Salon I-VI
Concurrent Session: Biology
7:30 p.m. – 7:50 p.m.
Jeffrey Shaman, Coriell Life Sciences
“Results and reflections of a real-world implementation of a pharmacogenomics-empowered comprehensive medication management (CMM) program”
7:50 p.m. – 8:10 p.m.
TBD
8:10 p.m. – 8:30 p.m.
Varuna Chander, Baylor College of Medicine
“Somatic mosaicism and cardiovascular disease: Uncovering hidden genetic etiology with clinical Implications”
8:30 p.m. – 8:50 p.m.
Eloi Schmauch, Massachusetts Institute of Technology, University of Eastern Finland, MIT and Harvard, Broad Institute
“Single-cell spatio-transcriptional dissection of human heart in health and coronary artery disease reveals cell-type-specific driver genes and pathways”
8:50 p.m. – 9:10 p.m.
Ethan Winkler, Barrow Neurologic Institute
“A cell resolution atlas of the human cerebrovasculature”
8:50 p.m. – 9:10 p.m.
Hilde Nelissen, Ghent University, Department of Plant Biotechnology and Bioinformatics / VIB Center for Plant Systems Biology
“Molecular CartographyTM reveals novel cell types and gene functions in the maize shoot apex”
June 9, 2022 (Morning)
7:30 a.m. – 9:00 a.m.
Waldorf Golf Pavilion
Breakfast
Floridian Ballroom Salon A-L
Plenary Session: Genetics II
Len Pennacchio, Lawrence Berkeley National Laboratory and DOE Joint Genome Institute, Chair
9:00 a.m. – 9:30 a.m.
Zach Lippman
Cold Spring Harbor Laboratory (CSHL) and Howard Hughes Medical Institute (HHMI)
9:30 a.m. – 10:00 a.m.
Alicia Zhou
Chief Science Officer, Color
10:00 a.m. – 10:20 a.m.
CA / University of East Anglia, UK
“Evolution of regulatory networks associated with traits under selection in cichlids”
10:20 a.m. – 11:00 a.m.
Coffee Break
Sponsor Promenades
11:10 a.m. – 11:30 a.m.
Konrad Karczewski (Abstract Selected)
The Broad Institute
Systematic single-variant and gene-based association testing of 3,700 phenotypes in 281,850 UK Biobank exomes
11:30 a.m. – 11:50 a.m.
Late breaking abstract, TBA
12:00 p.m. – 1:00 p.m.
Bonnet Creek Ballroom Salon I-VI
Silver Sponsor Workshop
12:00 p.m. – 1:30 p.m.
Outdoor Waldorf Promenade
AGBT Lunch
June 9, 2022 (Afternoon)
Floridian Ballroom Salon A-L
Plenary Session: Technology II
John McPherson, University of California, Davis, Chair
1:30 p.m. – 2:00 p.m.
Fei Chen
The Broad Institute of MIT and Harvard
2:00 p.m. – 2:30 p.m.
TBA
2:30 p.m. – 2:50 p.m.
TBA
2:50 p.m. – 3:20 p.m
Floridian Ballroom Foyer
Coffee Break
3:20 p.m. – 3:50 p.m.
Ghamdan Al-Eryani (Abstract Selected)
Garvan Institute of Medical Research
“Multi-omic integration of single-cell and spatial RNA and protein analysis identifies novel tumor-infiltrating lymphocyte phenotypes”
3:50 p.m. – 4:10 p.m.
Late breaking abstract, TBA
4:10 p.m. – 4:15 p.m.
CLICK2WIN Winner Announced
4:15 p.m. – 4:30 p.m.
Closing Comments and Meeting Feedback
6:00 p.m. – 11:00 p.m.
Waldorf Golf Pavilion
Farewell Dinner Party
Mardi Gras Theme
Join us at AGBT’s flagship event for bringing together global leaders, researchers, and innovators.
