2023 Agenda

Hollywood, Florida

Sunday, February 5, 2023

Transfers 1:00 p.m. – 8:00 p.m.

Fort Lauderdale–Hollywood International Airport (FLL)

12:00 p.m. – 7:00 p.m.

Meeting Registration / Hospitality Desk

Grand Foyer

Monday, February 6, 2023

Transfers 7:00 a.m. – 4:00 p.m.

Fort Lauderdale–Hollywood International Airport (FLL)

8:00 a.m. – 7:00 p.m.

Meeting Registration / Hospitality Desk

Grand Foyer

10:00 a.m. – 4:00 p.m.


Grand Ballroom

10:00 a.m. – 11:00 a.m.

McDonnell Genome Institute, Washington University

Human Pangenome Reference Consortium (HPRC) Workshop

Ting Wang, Benedict Paten, Karen Miga

1:00 p.m. – 4:00 p.m.

Bionano Genomics

Adam Smith, Alexander Hoischen, Klint Rose, George Vacek, Erik Holmlin, Alka Chaubey, Alex Hastie, Mark Oldakowski, Marc Meyers, Damla Senol Cali, Sheila Purim

“It’s time we all move forward. Join the Bionano Pre-Conference Workshop to see how”

Scientific Program

Plenary Session:

Genomics I (Eric Green, National Human Genome Research Institute, Chair)

Grand Ballroom

5:00 p.m. – 5:10 p.m.

Opening Remarks

5:10 p.m. – 5:40 p.m.

Dame Sue Hill, Chief Scientific Officer, NHS England

Harnessing the potential of genomic medicine in the NHS in England”

5:40 p.m. – 6:10 p.m.

Pardis Sabeti, Broad Institute of MIT and Harvard

“Sentinel: pandemic preemption in the genomic and information age”

6:10 p.m. – 6:30 p.m.

Christopher Mason, (Abstract Selected) Weill Cornell Medicine

“The Spatial Atlas of Human Anatomy (SAHA) Project: A High content spatial map of the human body”

6:30 p.m. – 6:50 p.m.

Varsha Rao, (Abstract Selected) Claret Bioscience

“Low-depth sequencing of cell-free DNA reveals disease-specific chromatin reorganization states”

6:50 p.m. – 7:10 p.m.

Hanlee Ji (Abstract Selected) Stanford University

“Single cell discovery of cancer point mutations and rearrangements with adaptive nanopore sequencing of transcripts”

7:15 p.m. – 10:00 p.m.

Welcome Reception-Havana Nights

South Lagoon Pool, Playa, Infinity Pool, South Palm Court

February 7, 2023 (Morning)

7:30 a.m. – 9:00 a.m.


South Palm Court

8:00 a.m. – 7:00 p.m.

Meeting Registration / Hospitality Desk

Grand Foyer

Plenary Session: 

Evolutionary Genomics (Beth Shapiro, University of California, Santa Cruz, Chair)  

Grand Ballroom

9:00 a.m. – 9:30 a.m.

Love Dalen, Centre for Paleogenetics, Stockholm, University

“A million-year genomic history of mammoth evolution”

9:30 a.m. – 10:00 a.m.

Carolyn Hogg, The University of Sydney

Conservation genomics: innovations, applications & where to next?”

10:00 a.m. – 10:25 a.m.

Elinor Karlsson, (Abstract Selected) UMass Chan Medical School

“Investigating the genetics of complex diseases in thousands of dogs through community science”

10:25 a.m. – 11:00 a.m.

Coffee Break

Sponsor Promenade

11:05 a.m. – 11:25 a.m.

Alexander Urban, (Abstract Selected) Stanford University

“Automatic detection of complex structural variation across diverse human populations and their enrichment within genes of neurodevelopmental pathways”

11:25 a.m. – 11:49 a.m.

Poster Flash Talks

February 7, 2023 (Afternoon)

12:00 p.m. – 1:30 p.m.

Gold Sponsor Workshop & Lunch

Great Hall 4-6

12:00 p.m. – 1:30 p.m.

Gold Sponsor Workshop & Lunch – NanoString

Jennifer Hart, Director, Technical Sales – NanoString Technologies

Holger Heyn, PhD, Single Cell Genomics, Team Leader – Centre For Genomic Regulation, Spain

Vikram Devgan, PhD, Senior Director, Product Management – NanoString Technologies

Joseph Beechem, PhD, Chief Scientific Officer and Senior Vice President of Research and Development – NanoString Technologies

Miranda E. Orr, PhD, Assistant Professor – Wake Forest University School of Medicine

“The power of NanoString spatial biology is here”

12:00 p.m. – 1:30 p.m.

AGBT Lunch

South Palm Court

1:30 p.m. – 3:30 p.m.

Poster Session with Coffee & Dessert

Regency Ballroom

Plenary Session:

Genomics II (John McPherson, University of California, Davis,Chair)

Grand Ballroom

3:30 p.m. – 4:00 p.m.

Benedict Paten, University of California, Santa Cruz

“Building the human pangenome reference”

4:00 p.m. – 4:30 p.m.

Duncan MacCannell, Centers for Disease Control and Prevention (CDC), Office of Advanced Molecular Detection (OAMD)

Building sustainable pathogen genomic surveillance: Lessons from the COVID-19 Response”

4:30 p.m. – 4:50 p.m.

Billy Lau, (Abstract Selected) Stanford University School of Medicine

“Nanopore sequencing of cell-free DNA for methylation-based breast cancer detection in a case-control cohort”

4:50 p.m. – 5:10 p.m.

Mitchell Vollger (Abstract Selected) University of Washington School of Medicine

“Comprehensive diploid genetic and epigenetic profiles with single-molecule precision”

February 7, 2023 (Evening)

5:15 p.m. – 7:15 p.m.

AGBT and Sponsor Dine Around

South Palm Court & South Lagoon Pool

Dine around is a fun way to meet, mingle, and enjoy different light bites at multiple locations

5:30 p.m. – 7:15 p.m.

Women’s Networking Event

33rd Floor Lounge

Concurrent Session:

7:30 p.m.– 9:30 p.m.

Cancer (Stacey Gabriel, Broad Institute of MIT and Harvard, Chair)

Grand Ballroom

7:30 p.m.– 7:50 p.m.

Edwin Cuppen, Hartwig Medical Foundation

“Pan-cancer whole genome comparison of primary and metastatic solid tumors”

7:50 p.m. – 8:10 p.m.

John Hickey, Stanford University

“Mechanisms of metaplastic progression to adenocarcinoma revealed by high-speed multiomic spatial phenotyping of FFPE human samples”

8:10 p.m.– 8:30 p.m.

Amanda Janesick, 10x Genomics

“High-resolution mapping of the breast cancer tumor microenvironment using integrated single cell, spatial and in situ analysis of FFPE tissue”

8:30 p.m. – 8:50 p.m.

Julia Kennedy-Darling, Akoya Biosciences

“High-speed multiomic spatial phenotyping of FFPE human cohorts to dissect mechanisms of environmental-conditioned metastasis”

8:50 p.m. – 9:10 p.m.

Rendong Yang, Northwestern University

“Super-enhancer analysis identifies IGF1R-AS1 as a novel oncogenic LncRNA in advanced prostate cancer”

9:10 p.m. – 9:30 p.m.

Netanel Loyfer, The Hebrew University of Jerusalem

“Deep whole-genome bisulfite sequencing of circulating cell-free DNA for monitoring patients with congestive heart failure”

Concurrent Session:

7:30 p.m. – 9:30 p.m.

Computational Biology (Mike Zody, New York Genome Center, Chair)

Great Hall 4-6

7:30 p.m. – 7:50 p.m.

Niall Lennon, Broad Institute of MIT and Harvard

“Ancestry calibration of PRS population variance using AoU participant data”

7:50 p.m. – 8:10 p.m.

Victoria Popic, Broad Institute of MIT and Harvard

“A deep learning framework for structural variant discovery and genotyping”

8:10 p.m. – 8:30 p.m.

Michael Schatz, Johns Hopkins University

“Genomics at scale with the NHGRI AnVIL”

8:30 p.m. – 8:50 p.m.

Valerie Schneider, NIH/NLM/NCBI

“The NIH Comparative Genomics Resource: A new ecosystem facilitating reliable comparative genomics”

8:50 p.m. – 9:10 p.m.

Yutaka Suzuki, The University of Tokyo

“Intensive single cell analysis for elucidating immune cell diversity among healthy individuals”

9:10 p.m. – 9:30 p.m.

Jiannis Ragoussis, McGill University

“Identification and characterization of SARS-Cov-2 defective interfering particles using direct RNA nanopore sequencing”

Starting at 9:30 p.m.


Sponsor Promenade

February 8, 2023 (Morning)

7:30 a.m. – 9:00 a.m.


South Palm Court

8:00 a.m. – 7:00 p.m.

Hospitality Desk

Grand Foyer

Plenary Session:

Genetics (Kim Doheny, Johns Hopkins University School of Medicine, Chair)

Grand Ballroom

9:00 a.m. – 9:30 a.m.

Alex Cagan, Wellcome Sanger Institute

“The Impossibility of Whales: somatic evolution across the tree of life”

9:30 a.m. – 10:00 a.m.

Solenne Correard, The University of British Columbia

“Building the path to equitable genomics care for Indigenous patients in Canada”

10:00 a.m. – 10:30 a.m.

Alicia Martin, Mass General Research Institute and Harvard Medical School

Genomics for the world: a comprehensive framework for genetic studies in diverse populations”


10:30 a.m. – 11:10 a.m.

Coffee Break

Sponsor Promenade

11:15 a.m. – 11:37 a.m.

Poster Flash Talks

February 8, 2023 (Afternoon)

12:00 p.m. – 2:15 p.m.

Silver Sponsor Workshops and Lunch

Great Hall 4-6

12:00 p.m.  –  1:00 p.m.

Silver 1 Sponsor Workshop and Lunch-Illumina

Niall Lennon, PhD, Senior Director of Translational Genomics, Institute Scientist, The Broad Institute of MIT and Harvard

Alex Aravanis, Chief Technology Officer, head of Research and Product Development, Illumina

Fiona Nohilly, Sr Manager, Product Marketing, Illumina

“NovaSeq X and innovations across the Illumina portfolio”

1:10 p.m.  –  2:10 p.m.

Silver 2 Sponsor Workshop and Lunch-10X

Augusto Tentori, Malte Kühnemund, Sarah Taylor, and Jill Herschleb, 10x Genomics

“Empowering impactful science with leading edge single cell, spatial, and in situ technologies”

12:00 p.m. – 2:00 p.m.

AGBT Lunch

South Palm Court

2:20 p.m. – 4:40 p.m.

Bronze Sponsor Workshops

Grand Ballroom

(Stephen Montgomery, Stanford University School of Medicine, Chair)

2:20 p.m. – 2:40 p.m.

Bronze 1 Sponsor – New England Biolabs

Kit Krishnan, Ph.D., Development Group Leader, Next Generation Sequencing, New England Biolabs

Maggie Heider, Ph.D., Development Scientist II, New England Biolabs

“Novel enzyme solutions enabling robust, high-performance library preparation from challenging to high-quality samples”

2:40 p.m. – 3:00 p.m.

Bronze 2 Sponsor – Element Biosciences

Matt Kellinger, PhD., Co-Founder & VP Biochemistry

Cloudbreak and Beyond: A roadmap for innovation”

3:00 p.m. – 3:20 p.m.

Bronze 3 Sponsor – BD Biosciences

Aruna Ayer, Ph.D., Director Single-Cell R&D, BD Biosciences

Single source for single-cell multiomics”

3:20 p.m. – 3:35 p.m.

Bronze 4 Sponsor – Resolve Biosciences, Inc

Jeroen Aerts, PhD

Spatial transcriptomics without compromising data quality”

3:35 p.m. – 3:50 p.m.

Bronze 5 Sponsor – Parse Biosciences

Charlie Roco, PhD, Cofounder, CTO

Broadening Access to Scalable Single Cell Sequencing”

3:50 p.m. – 4:05 p.m.

Bronze 6 Sponsor – Beckman Coulter Life Sciences

Ros Jackson, Ph.D., Director Scientific Research, Illumina

Calvin Cortes, MPH, MBA, Biomek NGeniuS Senior Product Manager, Beckman Coulter Life Sciences

“Harnessing the power of automation: Illumina DNA Prep Kit + Biomek NGeniuS Next Generation Library Prep System”

4:05 p.m. – 4:20 p.m.

Bronze 7  Sponsor – Roche Sequencing and Life Science

Mariana Fitarelli Kiehl, PhD., Senior Applications Scientist, Roche Sequencing & Life Science

“Single-tube total nucleic acid library preparation for FFPE: A combined method for DNA and RNA”

4:20 p.m. – 4:32 p.m.

Bronze 8 Sponsor – Watchmaker Genomics

Heather Maasdorp, Director of Global Support

“Advancing NGS library preparation using cutting-edge enzyme engineering approaches”

4:32 p.m. – 4:44 p.m.

Bronze 9 Sponsor – Singular Genomics

Eli Glezer, CSO, Founder

“Rapid SBS on the G4 sequencer: expanded capabilities and new applications”

4:45 p.m. – 6:10 p.m.

Poster Session and Wine & Cheese Reception

Regency Ballroom

February 8, 2023 (Evening)

6:15 p.m. – 7:25 p.m.

AGBT Dinner

South Lagoon Pool, South Palm Court & Monkitail Terrace

Concurrent Session:

7:30 p.m.– 9:30 p.m.

Technology (Chris Mason, Weill Cornell Medicine, Chair)

Grand Ballroom

7:30 p.m.– 7:50 p.m.

Andrew Adey, Oregon Health & Science University

“High-throughput, robust single-cell DNA methylation profiling with sciMETv2”

7:50 p.m. – 8:10 p.m.

Joseph Beechem, NanoString

“Path to the holy grail of spatial biology: spatial single cell whole transcriptomes using ultra-high plex spatial molecular imaging”

8:10 p.m. – 8:30 p.m.

Brian Hilbush, Veranome Biosystems/Applied Materials

“A highly robust LISH-LnR workflow for subcellular in-situ single-cell spatial transcriptomic profiling of human liver tissue”

8:30 p.m.– 8:50 p.m.

Kunal Jindal, Washington University School of Medicine

“Multiomic lineage tracing to dissect fate-specific gene regulatory programs”

8:50 p.m.– 9:10 p.m.

Heonseok Kim, Stanford University

“Highly parallelized single cell modeling and phenotyping of cancer mutations with transcript informed CRISPR engineering”

9:10 p.m.– 9:30 p.m.

Kaile Wang, MD Anderson Cancer Center

“Archival single cell sequencing reveals persistent subclones over years to decades of DCIS progression”

Concurrent Session:

7:30 p.m.– 9:30 p.m.

Biology (Penelope Bonnen, Baylor College of Medicine, Chair)

Great Hall 4-6

7:30 p.m. – 7:50 p.m.

Iraad Bronner, Wellcome Sanger Institute

“Combined Oxford Nanopore and PacBio sequencing of M. musculus for de-novo telomere-to-telomere genome assembly”

7:50 p.m.– 8:10 p.m.

JangKeun Kim, Weill Cornell Medicine

“Inspiration4: Comprehensive and integrative single cell multi-omics analysis of the immune system of SpaceX Inspiration4 mission crews”

8:10 p.m. – 8:30 p.m.

Cindy Lawley, Olink

“Empowering genomics with proteomics: Therapeutic target and biomarker discovery leveraging large population cohorts like the UK Biobank”

8:30 p.m.– 8:50 p.m.

Shawn Levy, Element Biosciences

“Avidity-based sequencing improves sensitivity and detection in metagenomic analysis”

8:50 p.m. – 9:10 p.m.

Lindsay Rizzardi, HudsonAlpha Institute for Biotechnology

“Identification of cis regulatory elements in DLPFC from Alzheimer’s donors using single cell multiomics”

9:10 p.m. – 9:30 p.m.

Robert Sebra, Icahn School of Medicine at Mount Sinai

“Isoform-resolved transcriptome reveals thousands of novel genes in human preimplantation embryos”

February 9, 2023 (Morning)

7:30 a.m. – 9:00 a.m.


South Palm Court

8:00 a.m. – 6:00 p.m.

Hospitality Desk

Grand Foyer

Plenary Session:

Biology (Federica Di Palma, Genome British Columbia, Chair)

Grand Ballroom

9:00 a.m. – 9:30 a.m.

Freda Miller, The University of British Columbia

“Using single cell approaches to understand how growth factors and stem cells build the brain”

9:30 a.m. – 10:00 a.m.

Judith Mank, The University of British Columbia

Y chromosomes matter”

10:00 a.m. – 10:30 a.m.

Beth Shapiro, University of California, Santa Cruz

“The story of the American bison in Three Acts”

10:30 a.m. – 11:10 a.m.

Coffee Break

Sponsor Promenades

11:10 a.m. – 11:30 a.m.

Peter Park, (Abstract Selected) Harvard Medical School

“Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements”

11:30 a.m.– 11:50 a.m.

Somasekar Seshagiri (Abstract Selected), AntlerA Therapeutics

“Next-gen snake anti-venom development through genome-guided single cell BCR-sequencing”

12:00 p.m. – 1:00 p.m.

Silver 3 Sponsor PacBio Workshop and Lunch

Great Hall 4-6

Christian Henry, CEO, PacBio

“The power of high accuracy sequencing”

12:00 p.m. – 1:30 p.m.

AGBT Lunch

South Palm Court

February 9, 2023 (Afternoon)

Plenary Session:

Technology (Martin Hirst, University of British Columbia, Chair)

Grand Ballroom

1:30 p.m. – 2:00 p.m.

Winston Timp, Johns Hopkins University

“Beyond assembly: the increasing flexibility of single-molecule sequencing technology”

2:00 p.m. – 2:30 p.m.

Karen Miga, University of California, Santa Cruz

“Expanding studies of global genomic diversity with complete, telomere-to-telomere (T2T) assemblies”

2:30 p.m. – 3:00 p.m.

Coffee Break

Grand Foyer

3:00 p.m. – 3:20 p.m.

Andrew Russell, (Abstract Selected) Broad Institute of MIT and Harvard

“Slide-tags: single-nucleus high-resolution multi-modal spatial genomics”

3:20 p.m. – 3:40 p.m.

Sanja Vickovic, (Abstract Selected) New York Genome Center

“Spatial host-microbiome sequencing”

3:40 p.m. – 4:00 p.m.

Samantha Maragh (Abstract Selected) National Institute of Standards and Technology (NIST)

“Outcomes of variant detection and quantitation from the first NIST Genome Editing Consortium Interlab Study”

4:00 p.m. – 4:15 p.m.

Click2Win Winner Announced

Closing Comments and Meeting Feedback

7:00 p.m. – Midnight

Farewell Dinner – Glow Nights & After Glow

Portico at Diplomat Landing